Squash Casserole Recipe

April 1, 2022

Squash Casserole is a favorite dish for family meals, holidays and more. Creamy, cheesy and topped with a buttery cracker topping, this squash casserole recipe is an all-time summer favorite.

Squash Casserole

Squash Casserole is most popular during the summer months, when most people grown squash in their gardens. However, Squash Casserole is not just limited to the summer months. Many people enjoy squash casserole year around. It is also a popular side dish severed for holidays, such as Thanksgiving, Christmas, and Easter.

If you have squash and not sure what to do with it, you may also like Sauteed Squash and Onions or Southern Fried Squash.

Can Squash Casserole be made ahead?

Squash Casserole can be made ahead and frozen or refrigerated. Just assemble the casserole, cover with plastic wrap, and store the casserole in the refrigerator or freezer until ready to bake. If you choose to freeze casserole, you should remove the casserole from the freezer the night before you plan to serve it and place it in the refrigerator overnight so it can thaw. When ready to bake the casserole, uncover it and bake it in preheated over at 350 for 35 minutes.

Equipment Needed:

Ingredients for squash casserole

How to make squash casserole.

Preheat oven to 350. Spray cooking dish with cooking spray. Slice squash into ½-inch slices. Discard the end pieces.

Chop onion. Melt 2 tablespoons of butter to a skillet over medium high heat.

Squash Casserole

Squash and Onion for Squash Casserole

Sauté squash and onion until tender. Usually about 7-8 minutes.

Meanwhile, combine sour cream, milk, mayonnaise, eggs, shredded cheese, salt and pepper in a large mixing bowl.

Squash Casserole

When Squash is tender transfer to baking dish. Pour cheese mixture over top of squash. Crumble a sleeve of buttery crackers over top of casserole. Melt the remaining 2 tablespoons of butter. Drizzle over top.

Place casserole in preheated over for 35 minutes or until the top is browned.

How to store leftover Squash:

Left over squash casserole can be covered and refrigerated for up to 4 days. you can reheat in the oven at 325-350 for 20-30 minutes, until the casserole hot throughout. However, the oven temperature and time to reheated will vary depending on the size of the casserole dish and the density of its contents.

Nutrition Facts

Serves 8

Amount Per Serving
% Daily Value*
Total Fat 24.9g32%
Cholesterol 88.9mg30%
Sodium 300.6mg13%
Total Carbohydrate 3.1g1%
Sugars 0.7g
Protein 6.9g14%
Vitamin A16%Vitamin C5%

More Casserole dishes:

Green bean Casserole

Broccoli and Cheese Casserole

Baked Macaroni and cheese

Never miss a recipe. Follow A Yummy Bite for more recipes.


Southern Squash Casserole

Squash casserole is a southern favorite. This easy to make casserole has tender squash and onions with a crunching buttery topping. That is sure to be a big hit at your next potluck.

  • Prep Time: 10 minutes
  • Cook Time: 35 minutes
  • Total Time: 45 minutes
  • Yield: 8 1x
  • Category: Side Dish
  • Cuisine: American


Units Scale
  • 4 tablespoon butter
  • 5 cups squash (about 4 squash)
  • ½ cup mayonnaise
  • ½ cup sour cream
  • 1 cup milk
  • ¼ teaspoon salt
  • ¼ teaspoon pepper
  • 2 large eggs
  • 1 cup shredded cheddar cheese
  • 1 small onion
  • 1 sleeve butter crackers (crumbled)


  1. Preheat oven to 350. Spray 9X13 casserole dish with cooking spray.
  2. Melt 2 tablespoons of butter in skillet over med-high heat. Add squash and onions. Sauté about 7 or 8 minutes until tender. Transfer to casserole dish.
  3. In a large mixing bowl add beaten eggs, shredded cheese, sour cream, and mayonnaise, milk, salt and pepper. Whisk together. Pour over squash and onion.
  4. Add crumbled crackers over top. Melt remaining butter. Drizzle over top. Cook for 35 minutes until top is browned.

Keywords: Squash, Squash Casserole, Side Dish,

Did you make this recipe?

Share a photo and tag us @a.yummy.bite.001. Hashtag #ayummybite — we can’t wait to see what you’ve made!

Search by catecory

Subscribe to Our Newsletter

Let's Keep In touch!

Sign up to receive awesome new recipes in your inbox, every week.

We don’t spam! Read our privacy policy for more info.